Quantum Biophotonics | NIST

Title: NIST Develops Advanced Quantum Biophotonics Technology for Precision Biology Measurements

Summary:
The National Institute of Standards and Technology (NIST) has developed a new quantum biophotonics technology that enables precise detection of faint light signals, opening up new possibilities in biology research and healthcare diagnostics. This technology combines advances in single-photon detection and novel data processing methods from the quantum optics community to achieve unprecedented sensitivity, capable of detecting light signals from a single molecule.

The potential applications of this technology are vast, particularly in the $10 billion annual market for low-light-level-based systems used in planar array and flow cytometry assays. Current detection methods lack the necessary sensitivity and reliability, especially when dealing with low analyte concentrations and changing bio-environmental conditions. NIST’s quantum biophotonics technology promises to provide independent verification of calibration and broader applicability.

NIST is currently developing a next-generation discriminative measurement system for flow cytometers in partnership with Lili Wang, MML, and has also developed the smallest, most sensitive detector for in-vivo detection of bioluminescence. These advancements have the potential to revolutionize biology research and healthcare diagnostics by enabling more precise and reliable measurements of faint light signals.

Source: https://www.nist.gov/programs-projects/quantum-biophotonics

Keywords: photon, metrology, biophotonics, quantum state, sensitivity

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